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Yahoo! My Yahoo! Mail More Yahoo! Services Account Options New User? Sign Up Sign In Help Yahoo! Search web search Home Singapore Asia Pacific World Business Entertainment Sports Technology Weekend Edition Australia China India Indonesia Japan Malaysia Philippines Thailand Vietnam ARV drugs greatly cut HIV risk ANN - Monday, November 29 Send IM Story Print Bangkok (The Nation-Thailand/ANN) - Taking antiretroviral (ARV) drugs could significantly reduce the chances of sexually active gay men getting HIV, the director of Chiang Mai University's Research Institute for Health Sciences (Rihes) Suwat Chariyalertsak said Saturday (November 27). His comment was made to coincide with World Aids Day on Wednesday (December 1). The clinical trial iPrEx (Pre-Exposure Prophylaxis Initiative), whose "ground-breaking" results were published in the New England Journal of Medicine, was a collaboration between Rihes and 11 other top research institutes in six countries. The trial, led by Dr Robert Grant from the University of California's Gladstone Institute of Virology and Immunology, had 2,499 volunteers in Peru, Ecuador, Brazil, South Africa, the United States and Thailand. The trial began to take volunteers in mid-2007, but Suwat said Thailand started research in Chiang Mai in early 2009 and continued until August this year. Following the end of medication given in all countries, the researchers would follow up on the volunteers until March next year, he said. The trial randomly assigned the volunteers - who were men who had sex with men, or transgender women who had sex with men - into two groups. The first group had to take one tablet of Truvada (a combination of two ARV medications, namely TDF and FTC) on a daily basis and the second group had to take a placebo. They found that, from the beginning until May 1, there were 36 people who became HIV-positive out of 1,251 volunteers who took Truvada, while 64 people out of 1,248 volunteers who took the placebo became HIV-positive. So, statistically it was concluded that the two ARV drugs could help reduce the risk of getting HIV by nearly 44 per cent - compared to the group that took the placebo. Suwat said in the cases of the volunteers who took the drugs regularly, the prevention rate went up. Suwat said iPrEx was the third study to find a way to prevent catching the HIV virus, following the HIV/Aids vaccine project that discovered a prevention rate of 31 per cent and the Caprisa 004 trial on tenofovir gel application in South Africa that found a prevention rate of 39 per cent. With the world still seeing about 2.7 million new infections a year, there was a lot more ongoing research involving more than 20,000 volunteers worldwide, he said. These projects should be finished within two to three years. Recommend Send IM Story Print Related Articles US base in spotlight as Japanese island reelects governor AFP - 49 minutes ago US-S.Korea naval exercises begin, China calls for talks AFP - 1 hour 20 minutes ago Hundreds pour into Thailand after Myanmar clashes Reuters - 2 hours 9 minutes ago China proposes emergency talks on Korea crisis Reuters - 2 hours 23 minutes ago US drone attack 'kills three militants in Pakistan' AFP - Monday, November 29 News Search Top Stories Experts split on global warming, highland malaria link International deal struck on Irish bailout Britain's Prince William happy to wait for crown Black Friday shows slight increase in US sales BA, Iberia face last hurdle over landmark merger More Top Stories » ADVERTISEMENT Most Popular Most Viewed Most Recommended Obama gets 12 stitches after 'elbow in the lip' Britain's Prince William happy to wait for crown Computer meltdown leaves Aussies without cash Crunch time at bluefin tuna meet Black Friday shows slight increase in US sales More Most Viewed » 'Naked' airport scanners may be 'dangerous' EU fines 11 airlines 800 million euros for air cargo cartel Pilgrims stone 'devil' as Muslims celebrate Eid World leaders scramble for funds to save the tiger US, S.Korea plan war games after N.Korean attack More Most Recommended » Elsewhere on Yahoo! Financial news on Yahoo! Finance Stars and latest movies Best travel destinations More on Yahoo! News Home Singapore Asia Pacific World Business Entertainment Sports Technology Weekend Edition Subscribe to our news feeds Top StoriesMy Yahoo!RSS » More news feeds | What are news feeds? Also on Yahoo! Answers Groups Mail Messenger Mobile Travel Finance Movies Sports Games » All Yahoo! Services Site Highlights Singapore Full Coverage Most Popular Entertainment Photos Yahoo! News Network Copyright © 2010 Yahoo! Southeast Asia Pte. Ltd. (Co. Reg. No. 199700735D). All Rights Reserved. Terms of Service | Privacy Policy | Community | Intellectual Property Rights Policy | Help Copyright © 2010 Yahoo! Southeast Asia Pte. Ltd. (Co. Reg. No. 199700735D). All Rights Reserved. Terms of Service | Privacy Policy | Community | Intellectual Property Rights Policy | Help

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