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Yahoo! My Yahoo! Mail More Yahoo! Services Account Options New User? Sign Up Sign In Help Yahoo! Search web search Home Singapore Asia Pacific World Business Entertainment Sports Technology Weekend Edition Top Stories Most Popular Photos Full Coverage Sitemap Smoking causes gene damage in minutes AFP - Sunday, January 16 Send IM Story Print Smoking causes gene damage in minutes WASHINGTON (AFP) - – Those first few puffs on a cigarette can within minutes cause genetic damage linked to cancer, US scientists said in a study released. In fact, researchers said the "effect is so fast that it's equivalent to injecting the substance directly into the bloodstream," in findings described as a "stark warning" to those who smoke. The study is the first on humans to track how substances in tobacco cause DNA damage, and appears in the peer-reviewed journal Chemical Research in Toxicology, issued by the American Chemical Society. Using 12 volunteer smokers, scientists tracked pollutants called PAHs, or polycyclic aromatic hydrocarbons, that are carried in tobacco smoke and can also be found in coal-burning plants and in charred barbecue food. They followed one particular type -- phenanthrene, which is found in cigarette smoke -- through the blood and saw it form a toxic substance that is known to "trash DNA, causing mutations that can cause cancer," the study said. "The smokers developed maximum levels of the substance in a time frame that surprised even the researchers: just 15-30 minutes after the volunteers finished smoking," the study said. "These results are significant because PAH diol epoxides react readily with DNA, induce mutations, and are considered to be ultimate carcinogens of multiple PAH in cigarette smoke," the study said. Lead scientist Stephen Hecht said the study is unique because it examines the effects of inhaling cigarette smoke, without interference from other sources of harm such as pollution or a poor diet. "The results reported here should serve as a stark warning to those who are considering starting to smoke cigarettes," Hecht said. Lung cancer kills about 3,000 people around the world each day, and 90 percent of those deaths are attributable to cigarette smoking. The research was funded by the National Cancer Institute. Recommend Send IM Story Print News Search Top Stories Europe meets under pressure to boost crisis fund British actress Susannah York dies aged 72: report Smoking causes gene damage in minutes Turkmenistan says ready for energy partnership with EU BP embarks upon Russian Arctic energy exploration deal More Top Stories » ADVERTISEMENT Most Popular Most Viewed Zsa Zsa Gabor has leg amputated to save life Smoking causes gene damage in minutes Breastfeeding study raises doubts over guidelines Delta mulls massive aircraft purchase British actress Susannah York dies aged 72: report More Most Viewed » More Most Recommended » Elsewhere on Yahoo! Financial news on Yahoo! Finance Stars and latest movies Best travel destinations More on Yahoo! News Home Singapore Asia Pacific World Business Entertainment Sports Technology Weekend Edition Subscribe to our news feeds Top StoriesMy Yahoo!RSS » More news feeds | What are news feeds? Also on Yahoo! Answers Groups Mail Messenger Mobile Travel Finance Movies Sports Games » All Yahoo! Services Site Highlights Singapore Full Coverage Most Popular Entertainment Photos Yahoo! News Network Copyright © 2011 Yahoo! Southeast Asia Pte. Ltd. (Co. Reg. No. 199700735D). All Rights Reserved. Terms of Service | Privacy Policy | Community | Intellectual Property Rights Policy | Help

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