InfoAnda - Landmark windpipe transplant uses patient stemcells

Pakistanis angry over detentions in Times Sq. case
Monday, May 24, 2010
ISLAMABAD – Relatives of three men detained by Pakistan for alleged links to the suspect in the attempted Times Square bombing say the men are innocent.
They

Taiwan denies boycotting Australian film festival
Thursday, August 6, 2009

AFP - Thursday, August 6TAIPEI (AFP) - - Taiwan's Beijing-friendly government on Wednesday denied boycotting an Australian film festival amid a row over the e

Merkel's support dips, regional ally resigns International
Thursday, September 3, 2009

By Sarah Marsh and Noah Barkin

BERLIN (Reuters) - Chancellor Angela Merkel suffered a double blow on Thursday as a senior party ally in east German

Minister seeks closure of anti-Berlusconi websites
Wednesday, December 16, 2009
ROME (AFP) - – The Italian government moved Tuesday to close down Internet sites encouraging further violence against Prime Minister Silvio Berlusconi, who

Asian markets mixed after Wall Street rally
Wednesday, March 18, 2009

By ELAINE KURTENBACH,AP Business Writer AP - Wednesday, March 18SHANGHAI - Asia's stock market rally seemed to be running out of steam Wednesday, despite an

Italy's top court to review shielding Berlusconi | 6 October 2009
Financial crisis ate your job? Try MySpace | Technology | | 17 January 2009
Mixed picture for retailers as US holiday season opens | 1 December 2008

Three killed in Hong Kong building collapse: reports | 30 January 2010

">Forum Views () ">Forum Replies ()

Read more with google mobile : Landmark windpipe transplant uses patient stemcells

Navigation Primary Navigation Home Singapore Asia Pacific World Business Entertainment Sports Technology Top Stories Most Popular Secondary Navigation Search Search: Landmark windpipe transplant uses patient stemcells AFP - 43 minutes ago PARIS (AFP) - - The pioneering transplant of a windpipe stripped of its cells and seeded with recipient stem cells has given a 30-year old Colombian woman a new lease on life, according to a study released Wednesday. The operation is the first of its kind, and shows that adult stem cells combined with re-engineered biological materials can "radically improve the ability of surgeons to treat patients with serious diseases," said Martin Birchall, a professor at the University of Bristol in Britain, and one of the study's authors. "We believe this success has proved that we are on the verge of a new age in surgical care," he said in a statement. The loss of a normal airway is devastating, and attempts to replace them have met with serious problems such as rejection by the immune system, the uncontrolled die-off of cells, called necrosis, and lethal bleeding. Claudia Castillo, stricken with tuberculosis, was facing the loss of her left lung after the tube-like branch connecting it to the trachea, or windpipe, became infected and collapsed beyond repair. Doctors explained that they could try an untested method to replace the ruined airway. "I was scared at the beginning because I was the first patient, but had confidence and trusted my doctors," Castillo said in a press release. "The possibility of avoiding the removal of my entire lung -- and instead replacing only my diseased bronchus -- represented a unique chance for me to return to a normal life." With her green light, a team of scientists and surgeons from Spain, Italy and Britain each contributed specialised knowledge to the task. Using a new technique developed at the University of Padua, scientists remove all the cells from the trachea of a 51-year old donor by essentially scrubbing it clean with a high-tech detergent solution. The next steps were to reconstitute the living tissue using Castillo's own cells, and graft them onto this biological scaffolding. Stem cells were obtained from her bone marrow, and cultivated in large numbers in Birchall's laboratory in Britain. They were then coaxed -- using growth-stimulating proteins -- into becoming structure-giving cartilage cells using a method originally devised for treating osteoarthritis. The surface of the donor's sterile trachea was seeded with these lab-grown cells using a bioreactor that allowed them to migrate into the tissue. Next the trachea was colonised with epithelial cells, which help the major airways keep clean by moving foreign objects away from the lungs. Finally, Castillo's damaged airway was surgically removed and replaced with the rebuilt windpipe. The operation was entirely successful, the authors report. "Within four days after transplantation, the graft was almost indistinguishable from adjacent normal bronchi," said Paolo Macchiarini, a professor at the University of Barcelona, where the operation was performed, and lead author of the study. And only ten days after surgery, Castillo left the hospital to rejoin her two children, aged 15 and four. "We think that this first experience represents a milestone in medicine and hope that it will unlock the door for a safe and recipient-tailored transplantation of the airway in adults and children," the authors conclude. For Castillo the results are already tangible: "I am now enjoying life and am very happy my illness has been cured," she said. Email Story IM Story Printable View Blog This Recommend this article Average (0 votes) Sign in to recommend this article » Most Recommended Stories » Enlarge Photo Undated file picture of 30-year old Colombian female recipient Claudia Castillo, taken at the Hospital clinic of Barcelona. The pioneering transplant of a windpipe stripped of its cells and seeded with recipient stem cells has given Castillo a new lease on life, according to a study released Wednesday. Most Popular – Top Stories Viewed Citigroup to slash 50,000 jobs, expenses worldwide Exercise, sleep cuts cancer risk: study Obama and McCain pledge 'new era of reform' Acinetobacter is emerging hospital superbug: study Earth would be heading to a freeze without CO2 emissions View Complete List » Search: Home Singapore Asia Pacific World Business Entertainment Sports Technology Top Stories Most Popular

Other News on Tuesday, 18 November 2008
Ten killed in Pakistani Taliban and tribal clashes: official
Israel renews blockade of Gaza crossings | International |
Barclays' proposed Gulf investors amend injection plan
Japan opposition seeks to force early election | International |
Afghans expect more talks soon with ex-Taliban | International |
Congo replaces army chief after defeats by rebels | International |
Russia, China to resume $25 billion loan talks
China denies attempting to get U.S. space data | International |
Experts: Half world faces water shortage by 2080
Iran speaker urges Iraq to resist U.S. pact: report | International |
Taiwan's Hua Nan Fin to write off more bad debts
More Iraqis travel abroad despite airport chaos | International |
Taiwan c.bnk to adjust rates to suitable levels
Hijacked Saudi tanker off Somali coast: US
Iran MPs approve Ahmadinejad's interior minister | International |
Taiwan stocks fall
China oil demand weakens due to global crisis
Sci Fi's Sanctuary a true Web-to-TV pioneer | Technology |
Hong Kong index falls 4.5 pct as bank shares hit
China picks up 3G pace, Mobile completes gear deals | Technology |
ADB says Asia economically dynamic despite crisis
China stocks tumble on profit-taking
Mazda: Ford to cut stake to 13 from 33.4 percent
Nicole Kidman says she's unsure about future acting | Entertainment |
Unhappy people watch more TV: study | Entertainment |
Reunited Kate and Leo lost on Revolutionary Road | Entertainment |
Rock stars tuning up for guitar documentary | Entertainment |
Australia makers vow to protect Aboriginal boy star | Entertainment |
Bon Jovi writing new songs for hits set | Entertainment |
Forest Whitaker and Sundance trying to save Newark | Entertainment |
Sci Fi's Sanctuary a true Web-to-TV pioneer | Entertainment |
Iraq PM tries to rally support for security pact
Archeologists say they found witch doctor skeleton
Hijacked Saudi tanker reaches Somalia | International |
Web 2.0 gives new tools to hate groups: experts
UN resumes food distribution in Gaza
Landmark windpipe transplant uses patient stemcells
Iraq PM says pact's critics want U.S. troops to stay | International |
Iranian parliament chooses new interior minister
Iraq announces date for long-delayed elections
Astronauts begin first spacewalk of Endeavour mission
Iran aims for 2009 launch of nuclear plant | International |
Saudi super-tanker taken to Somali pirate lair
UN to hear Croatia genocide claim against Serbia:
US financial rescue package 'not a panacea': Paulson
Brewer InBev completes takeover of Anheuser-Busch
Accused Syrian arms dealer not a Spanish spy: U.S. | International |
Russia coma reporter had received death threats | International |
Seoul shares open higher but quickly lose gains
Obama's rise forces Brazil to look at racial divide | International |
Obama vows to engage world on climate change
South Korean won rises early, firmer stocks help
Obama vows to engage world on climate change
NATO chief calls for more non-US troops in Afghanistan
Israel renews blockade of Gaza crossings | International |
Schwarzenegger opens climate change summit
Top US military officer: Taliban gains upper hand
Japan's Mitsubishi UFJ posts 64 percent profit drop
World frets about piracy, ignores Somalis' plight: group | International |
Crisis could mean bargains for China
US, Iraq differ on Iranian meddling in military pact
India sees growth accelerating to 9 pct next year
Tech firms turn to social media to reach consumers | Technology |
China calls for US economic talks to continue under Obama
Gulf War syndrome is real: US panel
Taiwan to hand out shopping coupons to boost economy: PM
Cuban responds to SEC, says no secrecy deal | Technology |
Europe stocks hit day high, helped by Wall St, oils
China approves US-Belgian beer merger
DoCoMo, KT Freetel to develop smart phone: report | Technology |
Bakrie squirms as crisis slams Indonesia
IBM says plans to acquire Transitive Corp | Technology |
Stars walk red carpet for Australia premiere | Entertainment |
Cool cat Travolta is a dog in latest role | Entertainment |
Jackson may be too unwell to travel to UK court | Entertainment |
Bond film piles on the millions in Britain | Entertainment |
For Wall-E director, art mixes well with commerce | Entertainment |
New U.N. art work raises controversy | Entertainment |
Opera may be coming to a movie theatre near you | Entertainment |
US commander hopes Obama moves quickly on Afghanistan
US arrests suspected Iranian agent in Iraq
Somali pirates seize Greek carrier | International |
Afghans pushing for a return to public execution
NASA tests "deep space Internet"
Suspected U.S. drone attack kills four in Pakistan | International |
Five killed in US missile strike in northwest Pakistan: officials
Malkin takes ice hockey puck to the face, sees scoring streak end
Strong earthquake strikes Panama | International |
Britain resumes high-level intelligence links with Syria: report
Obama girls visit their future White House home
Iraq PM says pact's critics want U.S. troops to stay | International |
Party politics undermine German economic defences
U.S. commander in Afghanistan has reconciliation plan | International |
China seeks to curb unrest amid finance crisis | International |
China's Hu puts off Cuba debt payments | International |
Texas jury indicts Cheney, Gonzalez in prison abuse case
Seoul shares halve losses; bashed techs bounce
North and South Koreans find cause for unity: Japan | International |
US forsees resususcitation of Doha round at APEC
Socialism and consumerism rub shoulders in Tripoli | International |
Sands blames Beijing and Macau for halt on casino project: report
Obama picks first African-American attorney general: media
S.Korea bond futures jump on BOK liquidity pledge
US museum head says Mexico should get Mayan jade
Microsoft to offer free security software | Technology |
Seoul shares drop but off low; LG Elec up
South Korea won edges up, ends 6-day losing streak
Mazda buys back chunk of own shares from Ford
Wynn backs government's travel curbs in Macau
Hollywood's Wizard of Oz lauded for stunning, sexy epic | Entertainment |
ADB lends 300 mln dlrs to China for railway line
Transporter 3 a new low for the action series | Entertainment |
China to build new oil, gas pipeline across Myanmar: state media
Nissan expects 'zero' second-half profits: CEO
Big changes in store for low-rated Daytime Emmys | Entertainment |
Stars walk red carpet for Australia premiere | Entertainment |
Italy fetes half century of Fellini's Dolce Vita | Entertainment |
Greece at new risk of being pushed off euro
Bodies of missing Tenn. mom, Jo Ann Bain, and daughter found
Female Breasts Are Bigger Than Ever
AMD Trinity Accelerated Processing Units Now in Volume Production
The Avengers (2012 film), made the second biggest opening- and single-day gross of all-time
AMD to Start Production of piledriver
Ivy Bridge Quad-Core, Four-Thread Desktop CPUs
Islamists Protest Lady Gaga's Concert in Indonesia
Japan Successfully Broadcasts an 8K Signal Over the Air
ECB boosts loans to 1 trillion Euro to stop credit crunch
Egypt : Mohammed Morsi won with 52 percent
What do you call 100,000 Frenchmen with their hands up
AMD Launches AMD Embedded R-Series APU Platform
Fed Should not Ignore Emerging Market Crisis
Fed casts shadow over India, emerging markets
Why are Chinese tourists so rude? A few insights

USD EUR - 1 year graph	VPN on MacOSX	BlogMeter 1.01