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Yahoo! My Yahoo! Mail More Yahoo! Services Account Options New User? Sign Up Sign In Help Yahoo! Search web search Home Singapore Asia Pacific World Business Entertainment Sports Technology Weekend Edition Top Stories Most Popular Photos Full Coverage Sitemap Seaweed defense offers clues against malaria AFP - Tuesday, February 22 Send IM Story Print WASHINGTON (AFP) - – Seaweed emits a natural chemical response to ward off fungi that would otherwise colonize an injured plant, a process that could help the search for anti-malaria drugs, a US scientist said Monday. Up to a million people per year die from malaria, which can be caused by the parasite Plasmodium falciparum, and new drugs are needed because the parasite is developing resistance to popular pharmaceuticals. "There are only a couple of drugs left that are effective against malaria in all areas of the world, so we are hopeful that these molecules will continue to show promise as we develop them further as pharmaceutical leads," said scientist Julia Kubanek, an associate professor at Georgia Tech. Researchers discovered the class of seaweed defense compounds, known as bromophycolides, by studying 800 species of seaweed off Fiji Island. One type in particular caught their attention, Callophycus serratus, "because it seemed particularly adept at fighting off microbial infections," said the study presented Monday at an international science conference in Washington. The molecules appeared in light-colored blotches on certain parts of the seaweed, and were visible with the help of a new technique known as desorption electrospray ionization mass spectrometry developed at the Georgia Tech's School of Chemistry and Biochemistry. "The alga is marshaling its defenses and displaying them in a way that blocks the entry points for microbes that might invade and cause disease," said Kubanek. "Seaweeds don't have immune responses like humans do. But instead, they have some chemical compounds in their tissues to protect them," she said. "We can co-opt these chemical processes for human benefit in the form of new treatments for diseases that affect us." However, more research needs to be done before the process can be turned into a drug for humans, and studies on mice are planned next. "As with other potential drug compounds, however, the likelihood that this molecule will have just the right chemistry to be useful in humans is relatively small," said the study. The research was funded by the National Institutes of Health as part of a long-term study of chemical signaling among organisms in coral reefs. In January, the World Health Organization launched a global plan to halt the spread of resistance to artemisinin, a key compound of new malaria drugs, warning that not acting would be "catastrophic." Resistance has emerged in areas on the Cambodia-Thailand border, while a spread to other areas in Cambodia, Myanmar, Thailand and Vietnam is suspected. The WHO said more than 175 million dollars in funding would be required for research and to contain the resistance in these areas. Recommend Send IM Story Print News Search Top Stories Moody's lowers Japan rating outlook to 'negative' Social media, cellphone video fuel Arab protests German minister in doctorate plagiarism scandal Machu Picchu victim of own success: UN 50 million 'environmental refugees' by 2020, experts say More Top Stories » ADVERTISEMENT Most Popular Most Viewed Oral sex linked to cancer risk Planet could be 'unrecognizable' by 2050, experts say Ink-jet printers inspire scientists to make skin Shell to sell African downstream assets for $1bln Machu Picchu victim of own success: UN More Most Viewed » More Most Recommended » Elsewhere on Yahoo! Financial news on Yahoo! Finance Stars and latest movies Best travel destinations More on Yahoo! News Home Singapore Asia Pacific World Business Entertainment Sports Technology Weekend Edition Subscribe to our news feeds Top StoriesMy Yahoo!RSS » More news feeds | What are news feeds? Also on Yahoo! Answers Groups Mail Messenger Mobile Travel Finance Movies Sports Games » All Yahoo! Services Site Highlights Singapore Full Coverage Most Popular Entertainment Photos Yahoo! News Network Copyright © 2011 Yahoo! Southeast Asia Pte. Ltd. (Co. Reg. No. 199700735D). All Rights Reserved. Terms of Service | Privacy Policy | Community | Intellectual Property Rights Policy | Help

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