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Japanese clone mouse from frozen cell, aim for mammoths
AFP - 1 hour 31 minutes ago
TOKYO (AFP) - - Japanese scientists said Tuesday they had created a mouse from a dead cell frozen for 16 years, taking a step in the long impossible dream of bringing back extinct animals such as mammoths.
Scientists at the government-backed research institute Riken used the dead cell of a mouse that had been preserved at minus 20 degrees Celsius (minus 4 degrees Fahrenheit) -- a temperature similar to frozen ground.
The scientists hope that the first-of-a-kind research will pave the way to restore extinct animals such as the mammoth.
The findings were published in the Proceedings of the National Academy of Sciences in the United States.
The scientists extracted a cell nucleus from an organ of the dead mouse and planted it into an egg of another mouse which was alive, leading to the birth of the cloned mouse, the researchers said.
"The newly developed technology of nucleus transfer greatly improved the possibility of reviving extinct animals," the research team led by Teruhiko Wakayama said in a statement.
The cloned mouse was able to reproduce with a female mouse, it added.
But the researchers said tough challenges remain ahead on how to restore extinct animals, which would require breeding with animals that are still alive.
To revive a mammoth, researchers would need to find a way to implant a cell nucleus of a mammoth into the egg of an elephant and then implant the embryo into an elephant's uterus, it said.
The elephant is the closest modern relative of the mammoth, a huge woolly mammal believed to have died out with the Ice Age.
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This handout picture, released by Japan natural science research center shows a cloned mouse (left) created with a new technology by using a frozen dead cell of a mouse
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