InfoAnda - HIV mutates at high speed to avoid immune system: study

Pakistanis angry over detentions in Times Sq. case
Monday, May 24, 2010
ISLAMABAD – Relatives of three men detained by Pakistan for alleged links to the suspect in the attempted Times Square bombing say the men are innocent.
They

Taiwan denies boycotting Australian film festival
Thursday, August 6, 2009

AFP - Thursday, August 6TAIPEI (AFP) - - Taiwan's Beijing-friendly government on Wednesday denied boycotting an Australian film festival amid a row over the e

Merkel's support dips, regional ally resigns International
Thursday, September 3, 2009

By Sarah Marsh and Noah Barkin

BERLIN (Reuters) - Chancellor Angela Merkel suffered a double blow on Thursday as a senior party ally in east German

Minister seeks closure of anti-Berlusconi websites
Wednesday, December 16, 2009
ROME (AFP) - – The Italian government moved Tuesday to close down Internet sites encouraging further violence against Prime Minister Silvio Berlusconi, who

Asian markets mixed after Wall Street rally
Wednesday, March 18, 2009

By ELAINE KURTENBACH,AP Business Writer AP - Wednesday, March 18SHANGHAI - Asia's stock market rally seemed to be running out of steam Wednesday, despite an

Faltering Iran talks to resume, deal possible | 21 October 2009
Top China delegate pulls out of IMF meet amid islands row | | 10 October 2012
Anger as Philippines says will skip Nobel ceremony | 9 December 2010

Japan's Prime Minister To Step Down | 3 June 2010

">Forum Views () ">Forum Replies ()

Read more with google mobile : HIV mutates at high speed to avoid immune system: study

Yahoo! My Yahoo! Mail Yahoo! Search Search: Sign InNew User? Sign Up News Home - Help Navigation Primary Navigation Home Singapore Asia Pacific World Business Entertainment Sports Technology Top Stories Most Popular Secondary Navigation Search Search: HIV mutates at high speed to avoid immune system: study AFP - Thursday, February 26 PARIS (AFP) - - A worldwide team of scientists said the human immunodeficiency virus (HIV) was swiftly evolving to avoid the body's immune defences, a phenomenon that adds to the challenge of crafting an AIDS vaccine. ADVERTISEMENT Mutations in HIV enable it to rapidly sidestep genetic variations that offer a better natural shield against the deadly pathogen, they said in a study released by the journal Nature. "Even in the short time that HIV has been in the human population, it is doing an effective job of evading our best efforts at natural immune control of the virus," said Oxford University researcher Philip Goulder. "This is high-speed evolution that we're seeing in the space of just a couple of decades." Goulder's team analysed the genetic codes and viral strain of 2,800 infected people in North America, the Caribbean, Europe, sub-Saharan Africa, Australia and Japan. Their big focus was on so-called human leukocyte antigen (HLA) genes. These control specialised proteins whose job is to act as a signaller against intruders. The proteins present little pieces of HIV to the body's heavy armour, T cells, which then seek out the virus and kill it. Since HIV was identified as the cause of AIDS, more than a quarter of a century ago, doctors have learnt that even though no-one appears to be naturally immune to the virus, people progress to the full-blown disease at different rates. Without antiretroviral drugs, some individuals may develop AIDS as little as a year after infection, while others take as long as two decades. The span depends largely on inherited luck, for there are variants of HLA genes that are far better at combatting HIV than others. A tiny difference in DNA can make a huge difference in holding back the virus. Goulder's team came across some bad news. They found that the virus is able to mutate when facing the more successful variants of these genes. This "escape mutation" is then transmitted on to the viral progeny and then handed on to the human population when another person becomes infected. "Where a favourable HLA gene is present at high levels in a given population, we see high levels of the mutation that enable HIV to resist this particular gene effect," said co-author Rodney Phillips in a press release issued by Oxford University. "The virus is outrunning human variation, you might say." The study adds a further complexity in the quest for an HIV vaccine, say the authors. Vaccine engineers will have to wrestle with different "escape mutations" in HIV that exist in distinct pools of populations. For instance, a highly favourable variant of HLA is called HLA-B*51. It is common among people in Japan -- and, as a result, two-thirds of infected people there have a strain of HIV which features the "escape mutation" for this variant. In Britain and Africa, though, HLA-B*51 is far less common. As a result, only between 15 to 25 percent of HIV-infected people have the "escape mutation" in their version of the virus. So it means that a successful HIV vaccine may have to take these geographical differences into account, as well as the stealthy, slippery mutability of the virus itself. "The implication is that once we have found an effective vaccine, it would need to be changed on a frequent basis to catch up with the evolving virus, much like we do today with the flu vaccine," said Goulder. AIDS first emerged in 1981 as a novel disease that destroys immune cells, exposing the body to opportunistic infections. HIV was identified as its source in 1983. Twenty-five million people have died of AIDS and an estimated 33 million people have HIV. The new paper focuses only on HIV's ability to sidestep natural immune systems. It did not address the virus' mutability towards anti-HIV drugs. Email Story IM Story Printable View Blog This Recommend this article Average (2 votes) Sign in to recommend this article » Most Recommended Stories » Enlarge Photo A researcher extracts fluid from a vial at an AIDS research facility in New York. A worldwide team of scientists said the human immunodeficiency virus (HIV) was swiftly evolving to avoid the body's immune defences, a phenomenon that adds to the challenge of crafting an AIDS vaccine. Most Popular – Top Stories Viewed HIV mutates at high speed to avoid immune system: study Iraqi police shoot dead four US soldiers: ministry At least nine dead as Turkish plane crash-lands in Amsterdam US launches 'stress test' for major banks On the bright side: scientists test 'happy' gene View Complete List » Search: Home Singapore Asia Pacific World Business Entertainment Sports Technology Top Stories Most Popular Copyright © 2009 Yahoo! Southeast Asia Pte Ltd. (Co. Reg. No. 199700735D). All Rights Reserved. Privacy Policy - Terms of Service - Community - Intellectual Property Rights Policy - Help

Other News on Thursday, 26 February 2009
Iran denies nuclear slowdown, sets big expansion | International |
Current Village People Granted Preliminary Injunction Against Former Lead Victor Willis
Rwandan troops leave Congo, stoking reprisal fears | International |
Mick Jagger's Ex-Wife Sued For Failing To Pay Ring Reward Money
Spray your tag on West Bank wall -- online | International |
Nazi death camp guard will be tried: prosecutor | International |
Polar regions found warming fast, raising sea levels | International |
Ugandan LRA rebels attack across CAR border: colonel | International |
Apple says Steve Jobs is still involved | Technology |
Nokia considering entering laptop industry: CEO | Technology |
Wealthy Americans Sue UBS To Keep Names Private
Spray your tag on West Bank wall -- online | Technology |
UAW President Urges Union To Support Ford Concessions
Netflix to offer streaming only plans in future | Technology |
Mass Layoffs Drop Slightly But Remain Highest On Record, Says Labor Dept.
Hide-and-seek death case irks Web users | Technology |
Update: Obama Names Locke As Commerce Secretary; Republicans Welcome Nomination
Poll Finds Muslims Opposed To Attacks On U.S. Civilians, But Want U.S. Troops Off Muslim Soil
Google joins EU antitrust case against Microsoft | Technology |
Hilton Rumored To Be Planning Layoffs In IT Dept; Adds 3 Luxury Hotels In Puerto Rico To Portfolio
U.S. top court rules for AT&T unit in antitrust case | Technology |
Environmentalists Praise Court Decision On Bush Administration Air Pollution Standards
Global chip market to fall 24 percent in 2009: Gartner | Technology |
Existing Home Sales Fall 5.3 Percent In January
Liquidators Secure Court Approval To Sell Fortunoff
Pension Plans For State Government, 2 Universities Missing $400M
Fan survives life with Rolling Stones | Entertainment |
Music to the ears of hospital patients | Entertainment |
Spidey heads to Broadway, with help from U2 pair | Entertainment |
Stomach Stapling In Britain Rose To 40 Percent In 2008 As Nation Struggled With Rising Obesity Rate
Peace negotiators urge change of attitude on Hamas
Bangladesh troop mutinies break out beyond Dhaka | International |
Hariri murder suspects languish in jail four years on
Turkish airliner crashes at Amsterdam airport, 9 dead | International |
The Obamas Decide On A Portuguese Water Dog As Newest Member Of First Family
Pakistan wants drones on table in US-Afghan review
Palestinians agree on prisoner release ahead of unity talks
Downturn to cost billions in aid to world's poor | International |
Obama to deliver address on Iraq Friday
Mexico vows more troops for drug war near U.S. border | International |
Puerto Rico to ship pesky monkeys to Iraq
Rohner steps down as UBS chief executive
Pakistan urges rethinking of U.S. drone attacks | International |
Palestinians seek $2.8 billion for rebuilding Gaza
Threat of oil spill menaces Russian Pacific island
Morocco calls back envoy in Iran over Bahrain
At least nine dead as Turkish plane crash-lands in Amsterdam
Isolation shields Afghanistan from financial crisis | International |
Terror-linked lawmaker faces arrest in Iraq
Iran says nuclear plant could start in months
U.S. will boost supplies for Afghan force | International |
Iranians in test run of first nuclear power plant
Younus falls short of record in drawn Test
Peace negotiators urge change of attitude on Hamas | International |
In third try, Obama names Gary Locke as Commerce Secretary
Die with us rebels tell Sri Lanka's refugees | International |
Australia seeks to cut animal gas emissions
U.S. law chief says Guantanamo "well-run"
Some US forces will face combat after Iraq pullout
Obama ready to set out Iraq withdrawal plan
Nokia considering entering laptop industry: CEO | Technology |
Final Exit Members Arrested, Charged With Assisting Suicide
Mexico extradites suspected drug gang leader to US
U.S.: China's Human Rights Record Worsened In 2008
US-TECH Summary
Poland says Obama team not focused on missile shield
FBI Agent Raids Offices Of University Of Florida Scientist Suspected Of Swindling NASA
Gannett slashes dividend to pay down debt
U.S. missile defence to complete test review by May
International Arms Dealer, Conspirator Sentenced To 30, 25 Years In U.S. Prison
Microsoft files patent suit against TomTom
U.S. Busts Mexican Drug Cartel; 755 Suspects Arrested
U.S. criticizes China and Russia in rights report
open to sale, partnership for search business
Florida Dad Kills Wife, 2 Daughters, Self
Arab League chief praises Obama, Mitchell
Feb 25 Highlights Of Low Points In U.S. Economy
Nokia considering entering laptop industry
Apple says Jobs on track to resume command as planned
House Passes $410 Billion Spending Bill
Spain's corruption probe widens
Wall Street Rallies Off Early Lows, Still Finishes Down
Spray your tag on West Bank wall -- online
Two Owners Of WG Trading Company Arrested For Securities, Wire Fraud
Global economic woes eroding IT spending: analysts
Ten killed in Amsterdam plane crash
Netflix to offer "streaming only" plans in future
UK opposition leader's disabled son dies
US top court rules for AT&T unit in antitrust case
Turkish jet crash kills nine in Amsterdam
Nokia considering entering laptop industry
Mobile email firm Visto buys rival from Motorola
Fan survives life with Rolling Stones | Entertainment |
Final Harry Potter film gets release date | Entertainment |
Clint Eastwood gets lifetime Palme d'Or | Entertainment |
Morgan Freeman sued over car crash | Entertainment |
Australia seeks to cut animal gas emissions
Thai PM vows to bring fugitive Thaksin back home
Slumdog child actors to get new homes in India | Entertainment |
Bangladesh border guard mutiny appears to spread
Pakistan braced for street protests after Sharif bar
Final Harry Potter film gets release date
Unrest reported at more Bangledesh guard posts
Weather forecast for the Asia-Pacific region
Bangladesh border guard mutiny spreads: police
Disputed Chinese relics fetch millions at YSL art auction
US sees South Asia rights problems
SKorea unveils new stimulus measures
China fumes as bronze relics sold at YSL auction
Report: NKorea builds underground fueling facility
FACTBOX-S.Korea takes steps to bring in more funds
Singer-guitarist leaves the Barenaked Ladies
Post 9-11 novel wins PEN/Faulkner prize
Thailand's auto workers lose jobs as economy worsens
Exhibition exposes sex slavery at Nazi camps
Seoul shares down; LG Display, Kia Motors tumble
Baghdad speakeasy defies the bombers
S.Korea won at 11-yr closing low despite gov't remarks
Europe's bison: prehistoric survivor with Achilles' heel
Pakistan c.bank sells 20 bln rupees of T-bills
US-ENTERTAINMENT Summary
S.Korea T-bond futures jump after c.bank comment
Final Harry Potter film gets release date
Chinese jet maker looks for foreign executives
Tibetan monk's HK trip shows Buddhism's divisions
Pakistani stocks open down but recover on IMF
Nick Mitchell has 'American Idol' judges laughing
Nissan to ease output cuts in March
Nobel laureate warns polls could ruin Aceh peace
Newly Discovered Species Of Fish Christened H. Psychedelica
Israeli rivals divided over Palestinian state
EU trio propose tougher list of Iran sanctions: report | International |
Tougher list of Iran sanctions proposed
Jennifer Lopez And Marc Anthony Sue U.K. Stroller Company For Unauthorized Image Use
Israeli rivals divided over Palestinian state | International |
Obama seeks new 250 billion bank bailout: report
American Rock Duo MGMT To Sue French President Nicolas Sarkozy's Party For Copyright Infringement
Olmert warns Iran over nuclear plant
Thousands protest in Pakistan over Sharif ruling | International |
Court Extends Britney Spears' Restraining Order Against Ex-Manager
HIV mutates at high speed to avoid immune system: study
Morgan Freeman's Crash Passenger Sues Him For Negligence, Denies Being Her Mistress
Taliban say want peace with Afghans, NATO troops out | International |
US launches 'stress test' for major banks
China decries U.S. criticism of its rights record | International |
Serbia charges 19 Bosnian officials with war crimes | International |
US-China ties needed to fight climate change
Obama to present first budget to Congress
Obama to seek $200 bln for war effort: report
US complains about China's human rights record
UK rules out charges against Pentagon hacker | Technology |
U.S. spy agency may get more cybersecurity duties | Technology |
Vodafone to offer Microsoft online services
Puppy love -- at your fingertips | Technology |
TomTom to contest Microsoft patent lawsuit
U.S. could reap billions taxing Web gambling: study | Technology |
Bill Clinton: Conditions Make Success Likely For Obama's Heathcare Reform Plan
Japanese teens addicted to cellphones: survey
Finns urged to check Web, curb guns after rampages | Technology |
Comcast Brings In Spanish Programs From Central, South America For U.S. Viewers
Coleman Suffers Another Blow; Minnesota Court Rejects Testimony Of Key Witness
Probe after 'miracle' Amsterdam plane crash
Illinois Psychiatric Hospital Under Investigation For Lax Patient Care
New violence erupts on French island Martinique
2-For-1 Offers Proliferate
Study Finds Many Cancers Preventable By Adopting Healthy Lifestyle
Senate Holds Hearing On Bush Administration 'Truth Commission' Next Week
Japanese teens addicted to cellphones: survey
Baltimore-Area Teen Becomes Ninth Pediatric Flu Death
Holder Impressed With 'Well-Run' Guantanamo Facilities But Determined To Shut It Down
FDA: Largest Indian Drugmaker Falsified Lab Test
China clears Wyeth milk powder: state media
Power-starved Kyrgyz start electricity rationing
Sri Lanka editor held, accused aiding rebel strike
Nepal PM vows to reinvestigate palace massacre
ASEAN leaders challenged on rights, economy
Fire damages Marriott hotel in Pakistan
NKorea's Kim Jong Il photographed smoking
Fire damages Marriott hotel in Islamabad
CORRECTED
Indonesia sentences Australian for teen sex
China's banking system stable amid global crisis: regulator
Japanese boy arrested over bomb plot
James Brown exhibit opens while museum plans await
Pakistani forex reserves fall to $10.16 bln
Up, up and away: Rare Superman comic for sale
S&P sees worst recession for Japan since WWII
China accuses Christie's of selling smuggled Chinese relics
Asian markets sour on recession fears
Rosie O'Donnell returns to TV in a Lifetime movie
S.Korea "hit by lightning" by E.Europe concerns-president
Mud, sweat and beers at Britain's maddest football match
Sands to fight ban on Macau ferry service
First Chen movie to hit screens after sex photos
Hong Kong exports dive by most in 50 years
German headscarf bans violates rights: HRW
Pakistan's PTCL net profit 5.3 bln rupees
India gives Oscar winner Rahman hero's welcome
U2 album leaked as label battles pirates
Stevie Wonder gets major award, praise from Obama
Indonesia's psychedelic fish named a new species
Teen Boy Escapes Father's Murder-Suicide Of Mom, Two Sisters
'Final Exit' Suicide Group Members Arrested, Charged With Assisting Suicide
2-For-1 Offers Proliferate
Greece at new risk of being pushed off euro
Bodies of missing Tenn. mom, Jo Ann Bain, and daughter found
Female Breasts Are Bigger Than Ever
AMD Trinity Accelerated Processing Units Now in Volume Production
The Avengers (2012 film), made the second biggest opening- and single-day gross of all-time
AMD to Start Production of piledriver
Ivy Bridge Quad-Core, Four-Thread Desktop CPUs
Islamists Protest Lady Gaga's Concert in Indonesia
Japan Successfully Broadcasts an 8K Signal Over the Air
ECB boosts loans to 1 trillion Euro to stop credit crunch
Egypt : Mohammed Morsi won with 52 percent
What do you call 100,000 Frenchmen with their hands up
AMD Launches AMD Embedded R-Series APU Platform
Fed Should not Ignore Emerging Market Crisis
Fed casts shadow over India, emerging markets
Why are Chinese tourists so rude? A few insights

USD EUR - 1 year graph	VPN on MacOSX	BlogMeter 1.01