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My Profile Top News Reuters top ten news stories delivered to your inbox each day. Subscribe You are here: Home > News > Technology > Article Home Business & Finance News U.S. Politics International Technology Internet Entertainment Sports Lifestyle Oddly Enough Environment Health Science Special Coverage Video Pictures Your View The Great Debate Blogs Weather Reader Feedback Do More With Reuters RSS Widgets Mobile Podcasts Newsletters Your View Make Reuters My Homepage Partner Services CareerBuilder Affiliate Network Professional Products Support (Customer Zone) Reuters Media Financial Products About Thomson Reuters Steve Jobs's cancer may have recurred: doctors Fri Jan 16, 2009 3:14pm EST Email | Print | Share | Reprints | Single Page [-] Text [+] By Anupreeta Das SAN FRANCISCO (Reuters) - Pancreatic cancer experts say they are puzzled by what is ailing Apple Inc Chief Executive Steve Jobs, because it is not clear how serious his health problems are or how directly they relate to his bout with cancer. Last week, Jobs said he had an easily treatable "hormonal imbalance" that was robbing his body of the proteins it needs. Then, on Wednesday, the 53-year-old CEO said his problems were "more complex" than originally thought, and he would take a medical leave of absence for six months. Doctors who have not treated Jobs say they can only speculate without hard information, but they said the tumor he was treated for in 2004 could have spread to another organ or resurfaced in the pancreas, requiring surgery or other treatment. Jobs could also be coping with side effects of that surgery that can be treated easily, they said. In 2004, Jobs was treated for a rare type of pancreatic cancer called an islet-cell, or neuroendocrine, tumor. Such tumors can be benign or malignant, but they usually grow slowly and are far less deadly than most pancreatic tumors. The American Cancer Society estimates that 37,680 Americans get pancreatic cancer each year, but few get islet-cell tumors of the kind Jobs had. The tumors are easily removed surgically but recur in roughly half of patients, said Dr. Roderich Schwarz, a cancer surgeon at the University of Texas Southwestern Medical Center in Dallas. Dr. Clay Semenkovich, an endocrinologist at Washington University in St. Louis, said in a telephone interview, "(Jobs) may have a new mass that's substantially altering his physiology and causing him to lose weight." WEIGHT LOSS The pancreas -- a spongy organ the size of a large banana -- produces enzymes used in digestion. Islet-cell tumors can cause over-secretion of hormones including insulin into the bloodstream, wreaking havoc on digestion and leading to drastic weight loss. Semenkovich said that could explain Jobs' "hormonal imbalance," but added that the limited information made it hard to say for sure. Apple's cryptic missives on Jobs' health have not deterred speculation -- sparked by his gaunt appearance at an Apple event in June 2008 -- that his cancer has returned. But his drastic weight loss could have other, less ominous explanations, doctors said. Jobs' surgery in 2004 is likely to have been the so-called Whipple procedure -- an extensive and complicated operation that involves several organs besides the pancreas, doctors agree. Weight loss is a common side effect, since a partial pancreas may not be able to effectively aid in the digestion of proteins, carbohydrates and fats. Continued... View article on single page Share: Del.icio.us Digg Mixx My Web Facebook LinkedIn Next Article: AMD to cut 1,100 jobs Also on Reuters In U.S. recession, poverty strikes middle class Slideshow Slideshow: Scenes from the Hudson River plane crash Sharks, not humans, most at risk in ocean More Technology News AMD to cut 1,100 jobs EU accuses Microsoft of curbing Web browser rivalry Financial crisis ate your job? Try MySpace Global digital music sales up 25 percent China makes arrests in Internet porn campaign More Technology News... Editor's Choice Slideshow A selection of our best photos from the past 24 hours. Slideshow Most Popular on Reuters Articles Video Madoff's fund may not have made a single trade New York fetes pilot who landed jetliner in river | Video UPDATE 1-New York fetes pilot who ditched jetliner in river Outrage in Chile at busty Virgin Mary models Circuit City to liquidate, shutter stores | Video Are Apple shares ripe for buying? 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Commentary Reuters Deals The global destination for corporate leaders, deal-makers and innovators Knowledge to Act Reuters.com: Help and Contact Us | Advertise With Us | Mobile | Newsletters | RSS | Interactive TV | Labs | Reuters in Second Life | Archive | Site Index | Video Index Thomson Reuters Corporate: Copyright | Disclaimer | Privacy | Professional Products | Professional Products Support | About Thomson Reuters | Careers International Editions: Africa | Arabic | Argentina | Brazil | Canada | China | France | Germany | India | Italy | Japan | Latin America | Mexico | Russia | Spain | United Kingdom | United States Thomson Reuters is the world's largest international multimedia news agency, providing investing news, world news, business news, technology news, headline news, small business news, news alerts, personal finance, stock market, and mutual funds information available on Reuters.com, video, mobile, and interactive television platforms. 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